发布人:     发布日期: 2020-09-11    浏览次数:

教授，博士生导师

办公地址：江苏省南京市玄武区卫岗1号，ylg8099官方网站理科楼A508

邮编：210095

办公电话：86-25-84396628

电子邮件：chaoli@njau.edu.cn

谷歌学术主页：https://scholar.google.com.hk/citations?user=MmfT5CkAAAAJ&hl=zh-CN

研究方向

主要从事新型基因组编辑技术研发以及植物基因组编辑技术开发与育种应用研究。

教育及工作经历

2020.07 – 至今 ylg8099官方网站，教授

2015.09 – 2020.07 中国科学院遗传与发育生物学研究所，遗传学，博士

2012.09 – 2015.06 石河子大学，遗传学，硕士

2008.09 – 2012.06 石河子大学，生物技术，学士

论文发表情况

2023年

1. Zhou S¹, Cai L¹, Wu H¹, Wang B, Gu B, Cui S, Huang X, Xu Z, Hao B, Hou H, Hu Y, Li C, Tian Y, Liu X, Chen L, Liu S, Jiang L, Wan J*. (2023) Fine tuning rice heading date through multiplex editing of the regulatory regions of key genes by CRISPR-Cas9. Plant Biotechnology Journal, DOI: 10.1111/pbi.14221.

2. Zhang A¹, Shan T¹, Sun Y¹, Chen Z, Hu J, Hu Z, Ming Z, Zhu Z, Li X, He J, Liu S, Jiang L, Dong X, Wu Y, Wang Y, Liu Y, Li C*, Wan J*. (2023) Directed evolution rice genes with randomly multiplexed sgRNAs assembly of base editors. Plant Biotechnology Journal, DOI: 10.1111/pbi.14156.

3. Wang C¹, Wang J¹, Lu J¹, Xiong Y¹, Zhao Z, Yu X, Zheng X, Li J, Lin Q, Ren Y, Hu Y, He X, Li C, Zeng Y, Miao R, Guo M, Zhang B, Zhu Y, Zhang Y, Tang W, Wang Y, Hao B, Wang Q, Cheng S, He X, Yao B, Gao J, Zhu X, Yu H, Wang Y, Sun Y, Zhou C, Dong H, Ma X, Guo X, Liu X, Tian Y, Liu S, Wang C, Cheng Z, Jiang L, Zhou J, Guo H, Jiang L, Tao D, Chai J, Zhang W, Wang H*, Wu C*, Wan J*. (2023) A natural gene drive system confers reproductive isolation in rice. Cell, 186, 3577-3592.

4. Wang P¹, Li Y¹, Liu Z¹, Li X¹, Wang Y, Liu W, Li X, Hu J, Zhu W, Wang C, Li S, Gu T, Xu D, Tang C, Wang Y, Li C, Zhang S, Wu J*. (2023) Reciprocal regulation of flower induction by ELF3α and ELF3β generated via alternative promoter usage. The Plant Cell, 35, 2095-2113.

2020年及以前

1. Zhu H¹, Li C¹, and Gao C*. (2020) Applications of CRISPR–Cas in agriculture and plant biotechnology. Nature Reviews Molecular Cell Biology, 21: 661–677. (ESI Highly Cited Papers)

2. Li C, Zong Y, Jin S, Zhu H, Lin D, Li S, Qiu JL, Wang Y*, Gao C*. (2020) SWISS: multiplexed orthogonal genome editing in plants with a Cas9 nickase and engineered CRISPR RNA scaffolds. Genome Biology, 21, 141.

3. Li C¹, Zhang R¹, Meng X¹, Chen S, Zong Y, Lu C, Qiu JL, Chen YH, Li J*, Gao C*. (2020) Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors. Nature Biotechnology, 38, 875-882. (Recommended in F1000Prime, ESI Highly Cited Papers)

4. Li C¹, Zong Y¹, Wang Y¹, Jin S, Zhang D, Song Q, Zhang R, Gao C*. (2018) Expanded base editing in crop plants using a Cas9-adenosine deaminase fusion. Genome Biology, 19, 59.

5. Zong Y¹, Song Q¹, Li C, Jin S, Zhang D, Wang Y, Qiu JL, Gao C*. (2018) Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A. Nature Biotechnology, 36, 950-953.

6. Zong Y¹, Wang Y¹, Li C, Zhang R, Chen K, Ran Y, Qiu JL, Wang D, Gao C*. (2017) Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion. Nature Biotechnology, 35, 438-440.

7. Li C, Zhang Y, Zhang K, Guo D, Cui B, Wang X, Huang X*. (2015) Promoting flowering, lateral shoot outgrowth, leaf development, and flower abscission in tobacco plants overexpressing cotton FLOWERING LOCUS T (FT)-Like gene GhFT1. Frontiers in Plant Science, 6, 454.

8. Guo D¹, Li C¹, Dong R, Li X, Xiao X, Huang X*. (2015) Molecular cloning and functional analysis of the FLOWERING LOCUS T (FT) homolog GhFT1 from Gossypium hirsutum L. Journal of Integrative Plant Biology, 57, 522-533.

科研项目

1. 江苏省杰出青年基金项目，SBK2023010234，植物基因组编辑技术开发与应用，2023.09 – 2026.08，在研，主持

2. 国家自然科学基金青年科学基金项目，32201227，植物高效小型化CRISPR/Cas基因组编辑系统的开发研究，2023.01 – 2025.12，在研，主持

3. 海南省崖州湾种子实验室揭榜挂帅项目，B21HJ1004，作物精准编辑技术研发与种质优化，2021.12 – 2024.12，在研，联合主持

4. 中国科协第六届青年人才托举工程，2020QNRC001，植物内源基因定向进化技术和策略的开发及应用，2020.09 – 2023.09，在研，主持

5. ylg8099官方网站高层次引进人才启动资金，2020-2025，主持

所获荣誉

2021.08，中国科学院优秀博士学位论文

2019.12，中国科学院大学朱李月华优秀博士生奖

2018.11，博士研究生国家奖学金

2018.07，中国科学院经理优秀奖

2016.03，新疆维吾尔自治区优秀硕士学位论文

2015.06，石河子大学优秀毕业研究生

2012.06，石河子大学优秀本科毕业论文